An effortless and comprehensive approach to burden of illness reviews
PLEASE READ THESE TERMS AND CONDITIONS CAREFULLY BEFORE USING THIS SITE
What's in these terms?
These terms tell you the rules for using our website www.heoro.com (our site).
Who we are and how to contact us
www.heoro.com is a site operated by Crystallise Limited (company number 07980921) whose registered office is at 19 Saffron Court, Southfields Business Park, Basildon, Essex SS15 6SS.
By using our site you accept these terms
By using our site, you confirm that you accept these terms of use and that you agree to comply with them.
If you do not agree to these terms, you must not use our site. We recommend that you print a copy of these terms for future reference.
There are other terms that may apply to you
If you make purchases from our site, our Terms and conditions of supply (http://www.sagepay.co.uk/policies/terms-of-use) will apply to the sales.
We may make changes to these terms
We amend these terms from time to time. Every time you wish to use our site, please check these terms to ensure you understand the terms that apply at that time.
We may make changes to our site
We may update and change our site from time to time. We will try to give you reasonable notice of any major changes.
We may suspend or withdraw our site
Our site is made available free of charge.
We do not guarantee that our site, or any content on it, will always be available or be uninterrupted. We may suspend or withdraw or restrict the availability of all or any part of our site for business and operational reasons. We will try to give you reasonable notice of any suspension or withdrawal.
You are also responsible for ensuring that all persons who access our site through your internet connection are aware of these terms of use and other applicable terms and conditions, and that they comply with them.
How you may use material on our site
We are the owner or the licensee of all intellectual property rights in our site, and in the material published on it. Those works are protected by copyright laws and treaties around the world. All such rights are reserved.
You must not use any part of the content on our site for commercial purposes without obtaining a licence to do so from us or our licensors.
You will, and will ensure that any of your employees, directors, consultants or agents comply fully with the Licence Agreement at Schedule 1 as you were the Licensee under the Licence Agreement and undertakes to only use this website and any content from this website in accordance with the provisions of the Licence Agreement.
Do not rely on information on this site
The content on our site is provided for general information only. It is not intended to amount to advice on which you should rely. You must obtain professional or specialist advice before taking, or refraining from, any action on the basis of the content on our site.
Although we make reasonable efforts to update the information on our site, we make no representations, warranties or guarantees, whether express or implied, that the content on our site is accurate, complete or up to date.
Our responsibility for loss or damage suffered by you
· We do not exclude or limit in any way our liability to you where it would be unlawful to do so. This includes liability for death or personal injury caused by our negligence or the negligence of our employees, agents or subcontractors and for fraud or fraudulent misrepresentation.
· Different limitations and exclusions of liability will apply to liability arising as a result of the supply of any products to you, which will be set out in our Terms and conditions of supply (http://www.sagepay.co.uk/policies/terms-of-use).
· You warrant that you are a business and not a consumer.
· We exclude all implied conditions, warranties, representations or other terms that may apply to our site or any content on it.
· We will not be liable to you for any loss or damage, whether in contract, tort (including negligence), breach of statutory duty, or otherwise, even if foreseeable, arising under or in connection with:
· use of, or inability to use, our site; or
· use of or reliance on any content displayed on our site.
· In particular, we will not be liable for:
· loss of profits, sales, business, or revenue;
· business interruption;
· loss of anticipated savings;
· loss of business opportunity, goodwill or reputation; or
· any indirect or consequential loss or damage.
We are not responsible for viruses and you must not introduce them
We do not guarantee that our site will be secure or free from bugs or viruses.
You are responsible for configuring your information technology, computer programmes and platform to access our site. You should use your own virus protection software.
You must not misuse our site by knowingly introducing viruses, trojans, worms, logic bombs or other material that is malicious or technologically harmful. You must not attempt to gain unauthorised access to our site, the server on which our site is stored or any server, computer or database connected to our site. You must not attack our site via a denial-of-service attack or a distributed denial-of service attack. By breaching this provision, you would commit a criminal offence under the Computer Misuse Act 1990. We will report any such breach to the relevant law enforcement authorities and we will co-operate with those authorities by disclosing your identity to them. In the event of such a breach, your right to use our site will cease immediately.
Which country's laws apply to any disputes?
If you are a consumer, please note that these terms of use, their subject matter and their formation, are governed by English law. You and we both agree that the courts of England and Wales will have exclusive jurisdiction except that if you are a resident of Northern Ireland you may also bring proceedings in Northern Ireland, and if you are resident of Scotland, you may also bring proceedings in Scotland.
If you are a business, these terms of use, their subject matter and their formation (and any non-contractual disputes or claims) are governed by English law. We both agree to the exclusive jurisdiction of the courts of England and Wales.
Schedule 1 - LICENCE AGREEMENT
U.S. National Library of Medicine (NLM) National Institutes of Health Department of Health and Human Services
LICENSE AGREEMENT FOR NLM DATA
WHEREAS, the National Library of Medicine was established by statute in order to assist the advancement of medical and related sciences, and to aid the dissemination and exchange of scientific and other information important to the progress of medicine and to the public health, (section 465 of the Public Health Service Act, as amended (42 U.S.C. section 286); and
WHEREAS, NLM has produced data (NLM data) that are useful in a variety of settings and, subject to available governmental funding, are available under this License; and
WHEREAS, NLM data may include abstracts provided by third parties for inclusion in NLM data, and use of the abstracts should be guided by the principles of fair use; and
WHEREAS, Licensee desires to use NLM data at its sole risk and at no expense to NLM;
NOW THEREFORE, it is mutually agreed as follows:
1. NONEXCLUSIVE RIGHT/PUBLIC INFORMATION
NLM hereby grants a nonexclusive right to the Licensee to use NLM data selected from Appendix A subject to the provisions/restrictions in this nonnegotiable License and its Appendices. The list of Licensees is public information.
2. REQUIRED INFORMATION
Licensee shall provide information related to the intended use of the licensed data to complete a License request. The Licensee shall update the information annually as requested by NLM.
3. PRICING
Currently NLM does not impose charges of any kind for data licensed under this License. Rates, if imposed by NLM, shall become effective after ninety (90)-days' notice published in the NLM Technical Bulletin (http://www.nlm.nih.gov/pubs/techbull/tb.html).
4. LIABILITIES AND WARRANTIES
A. Licensee assumes all liability for its negligent acts and omissions or any injury or damage to the U.S. Government resulting from Licensee's use of the NLM data, and shall indemnify the Government against liability for any claim resulting from such use by Licensee.
B. NLM represents that its data provided under this License were formatted with a reasonable standard of care, but makes no warranties express or implied, including no warranty of merchantability or fitness for particular purpose, regarding the accuracy or completeness of the data or that the machine-readable copy is error free. Therefore, Licensee agrees to hold NLM and the U.S. Government harmless from any liability resulting from errors in the licensed data. NLM
disclaims any liability for any consequences due to use, misuse, or interpretation of information contained or not contained in the licensed data.
C. Licensee assumes full responsibility for all costs associated with its access to, preparation, maintenance, and overall use of the NLM data.
5. STANDARDS OF QUALITY
A. Licensee shall provide high caliber products/services/applications (including but not limited to scholarly, research, corporate, governmental, and commercial use) making use of the data licensed under this License.
B. Licensee shall provide the following statement to users of its products/services/applications who have access either to the original data licensed under this License or information/data derived from the original licensed data: “NLM represents that its data were formulated with a reasonable standard of care. Except for this representation, NLM makes no representation or warranties, expressed or implied. This includes, but is not limited to, any implied warranty of merchantability or fitness for a particular purpose, with respect to the NLM data, and NLM specifically disclaims any such warranties and representations.”
C. Licensee shall:
1.[The following does not apply to Catfile, CatfilePlus, and Serfile data] Prominently label each NLM record so as to identify the NLM database and NLM as the source if discrete NLM records can be retrieved in combination with discrete records from other sources. Attribution to NLM should be at the most granular level possible. Recommended wording example: “From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.”)
2.[The following does not apply to Catfile, CatfilePlus, and Serfile data] Prominently label the NLM content to identify the NLM-derived elements clearly and NLM as the source when complete or partial NLM records are merged or displayed with data from other sources to create a composite record. Attribution to NLM should be at the most granular level possible. Recommended wording example: “Article title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.”
3.Make known, in a suitably clear and conspicuous manner:
a. The currency of the NLM data used in its products/services/applications, based on the date NLM released the most recent data file used (i.e., the date NLM put the files on its server).
b. That the products/services/applications may not reflect the most current and accurate biomedical/scientific data available from NLM if Licensee does not use updated data that NLM makes available during a calendar year (that is, there is no intention to update so that a static version of data is used).
4. Characterize accurately the capabilities of Licensee's products/services/applications and the purpose for which the NLM data or information/data derived from NLM data is suitable and appropriate.
5. Provide NLM with free and unobstructed access to Licensee’s products/services/applications using NLM data for testing/quality assurance purposes.
6. Complete a quality assurance self-assessment evaluation or another quality assurance evaluation mechanism upon request by NLM.
D. Licensee shall abide by the requirements in Appendix B if Licensee’s products/services/applications are not based upon a static version of the data. If Licensee updates its products/services/applications on a regular or irregular basis by adding files containing new, revised, and deleted records provided by NLM, the requirements in Appendix B apply.
6. THIRD PARTIES
Licensee may redistribute all or partial data licensed under this License, or information/data derived from data licensed under this License, to a third party. In this case, Licensee shall include in its agreements with third parties provisions to ensure that the third party use complies with all provisions of this License and its Appendices. In particular, use with updates resulting from duplication, sale, or redistribution of NLM data by Licensee or its users must also conform to the requirements listed in Appendix B.
7. ATTRIBUTION
A. Licensee shall acknowledge NLM as the source of the data licensed under this License in a suitably clear and conspicuous manner. This pertains to all varieties of electronic or printed products/services/applications including those which may consist of: 1) only data licensed from NLM; 2) complete or partial NLM-provided records merged or displayed with data from other sources, or 3) information/data derived from data licensed from NLM.
Recommended wording examples for attribution are: “From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.” “Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.” “Protein-gene relationships mined from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.”
B. Licensee shall provide the following statement to users of its products/services/applications who, in turn, may redistribute or retransmit the records or derived data:
“All complete or parts of U.S. National Library of Medicine (NLM) records that are redistributed or retransmitted must be identified as being derived from NLM data.” Recommended wording examples for attribution are: “From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.” “Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.” “Protein-gene relationships mined from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.”
C. Licensee shall not indicate or imply that NLM has endorsed Licensee or its products/services/applications.
D. Licensee shall properly use registration symbols (http://www.nlm.nih.gov/pubs/factsheets/trademarks.html) when referring to NLM databases,
systems, and products. Licensee must name their products/services/applications in a fashion that clearly distinguishes them from NLM-produced databases.
8. COPYRIGHT AND FAIR USE
A. NLM data are produced by a U.S. Government agency and include works of the United States Government that are not protected by U.S. copyright law but may be protected by non-US copyright law, as well as abstracts originating from publications that may be protected by U.S. or non-US copyright law.
B. NLM assumes no responsibility or liability associated with Licensee’s use of copyrighted material, including transmitting, reproducing, redistributing, or making commercial use of the data. NLM does not provide legal advice regarding copyright (http://www.copyright.gov/circs/circ1.html), fair use (http://www.copyright.gov/fls/fl102.html), or other aspects of intellectual property rights. Persons contemplating any type of transmission or reproduction of copyrighted material such as abstracts are advised to consult legal counsel.
C. Licensee shall inform its users that the duplication, sale, or redistribution of data obtained under this License must conform to fair use guidelines and copyright law.
Licensee is required to provide the following statements to users of its products/services/applications in a suitably clear and conspicuous manner:
“NLM data are produced by a U.S. Government agency and include works of the United States Government that are not protected by U.S. copyright law but may be protected by non-US copyright law, as well as abstracts originating from publications that may be protected by U.S. copyright law.”
“ NLM assumes no responsibility or liability associated with use of copyrighted material, including transmitting, reproducing, redistributing, or making commercial use of the data. NLM does not provide legal advice regarding copyright, fair use, or other aspects of intellectual property rights. Persons contemplating any type of transmission or reproduction of copyrighted material such as abstracts are advised to consult legal counsel.”
D. NLM does not authorize third party Web-crawling of sites that mount versions of data licensed per this License.
9. CHANGES TO DATA OR MEDIUM
NLM reserves the right to change the type, format, and distribution medium for data made available under this License. If possible, NLM will inform Licensee in advance of such changes at least thirty (30) days before the data are distributed.
10. REPORTS
Within thirty (30) days after requested by NLM, Licensee shall provide a brief report summarizing the purpose and progress of the use of the NLM data. Licensee must provide NLM with a copy of or free access to any paper that is published about research, commercial, or other use of the licensed NLM data.
11. TRANSFERABILITY OF LICENSE
With NLM’S approval in writing, Licensee may transfer this License to a successor that has acquired substantially all of Licensee's business, the particular product line, or the particular research use for which this License has been entered into by Licensee. Succession shall include, but not be limited to, acquisition, merger, change of corporate name, or change in the make-up, organization, or identity of Licensee. The transferee shall also be subject to all of the conditions stated in this License. Licensee shall notify NLM in writing within ninety (90) days after such a transfer occurs. NLM may, at its discretion, require that a new License be signed by the successor.
12. DURATION AND TERMINATION
A. Licensee shall submit information and reports noted in Clauses 2 and 10 of this License, non-receipt of which is cause for termination of the License.
B. This License shall be effective until terminated by one of the parties upon thirty (30) days’ written notice to the other party. Licensee's failure to abide by the terms of the License shall be grounds for termination of the License. If Licensee cures the failure to the reasonable satisfaction of NLM within sixty (60) days of the date of the notice of revocation, this License shall continue in effect. Neither the U.S. Government nor its employees shall be liable or responsible to Licensee in any manner whatsoever for damages of any nature whatsoever arising from the termination of this License.
C. In the event that any provision of this License is determined to violate any law or is unenforceable, the remainder of the License shall remain in full force and effect.
D. Licensee may add other data covered under this License and listed in Appendix A to an existing License upon written request and written approval from NLM. Licensee may discontinue licensing data covered under this License and listed in Appendix A upon written notification to NLM. The License remains in effect as long as at least some NLM data covered by the License are licensed.
E. [The following does not apply to Catfile, CatfilePlus, and Serfile data] Licensee shall take the following actions when data are no longer licensed under this License or when the License is terminated:
1. Discontinue use of any promotional or other materials that refer to such data within thirty (30) days, and
2. Cease use of data or information/data derived from data licensed under this License in all applications no later than ninety (90) days. Following that, Licensee must promptly destroy and erase all data obtained under this License as well as any data contained in any derivative applications under Licensee’s control.
13.NOTIFICATIONS
NLM shall announce changes to the License in the NLM Technical Bulletin (http://www.nlm.nih.gov/pubs/techbull/tb.html). In addition, information concerning policy and
data changes will be transmitted via e-mail and subsequently available from NLM’s Web page for Licensees (http://www.nlm.nih.gov/bsd/licensee).
14.AMENDMENTS
This License and its Appendices constitute the entire understanding between NLM and Licensee and no modification of this License shall be binding upon either party unless it is published in the NLM Technical Bulletin (http://www.nlm.nih.gov/pubs/techbull/tb.html).
15.APPENDICES:
The License includes the following Appendices which must be read before accepting the License.
Appendix A: Data Covered by the License Agreement
Appendix B: Requirements for Use of NLM Licensed Data with Updates
Appendix C: MEDLINE®/PubMed® Minimal Data Element Set
APPENDIX A: DATA COVERED BY THE LICENSE AGREEMENT
The License covers the following data and does not include software. After accepting the License and its Appendices, prospective licensees complete a license request form to select data they initially want to license. Once a license is established, a licensee may add other data covered under this License upon request to NLM.
BIOMEDICAL JOURNAL CITATION DATA
MEDLINE®/PubMed® (http://www.nlm.nih.gov/databases/journal.html, includes MEDLINE and most other non-MEDLINE records that reside in PubMed)
CATALOGING/BIBLIOGRAPHIC DATA (http://www.nlm.nih.gov/databases/catser.html)
Catfile
CatfilePlus
Serfile
TOXICOLOGIC/CHEMICAL DATA
CCRIS (http://www.nlm.nih.gov/pubs/factsheets/ccrisfs.html)
ChemIDplus® Subset (http://www.nlm.nih.gov/databases/chemidplus.html)
GENE-TOX (http://www.nlm.nih.gov/pubs/factsheets/genetxfs.html)
HSDB® (http://www.nlm.nih.gov/pubs/factsheets/hsdbfs.html)
TOXLINE® Subset (http://www.nlm.nih.gov/databases/databases_toxline.html)
APPENDIX B: REQUIREMENTS FOR USE OF NLM LICENSED DATA WITH UPDATES
Appendix B applies when Licensees’ products/services/applications are not based upon a static version of the data, but rather are updated on a regular or irregular basis by adding new records, replacing revised records, and removing deleted records supplied by NLM. Appendix B applies whether or not the updated products/services/applications are available to a limited number of people or available to many people, and whether or not there is restricted or unrestricted use of the updated products/services/applications.
Each item below applies for use of licensed MEDLINE®/PubMed® data. Database name(s) in brackets following a clause indicates that the clause also applies for use of that data.
Licensee shall:
1.Comply with the following data display requirements:
A. If the product/service/application is a citation retrieval system displaying MEDLINE/PubMed citation data and the product/service/application does not provide a direct electronic link to the corresponding record in PubMed at NLM, at least the minimal set of data elements listed in Appendix C for each record must be displayed. If the product/service/application is a citation retrieval system displaying MEDLINE/PubMed citation data and the product/service/application does provide a direct electronic link to the corresponding record in PubMed at NLM, there is no minimal set of data elements required for display.
B. If the product/service/application retrieves data derived from MEDLINE/PubMed records and does not provide a direct electronic link to the underlying record(s) in PubMed, at least the NLM PMID(s) associated with the underlying citation(s) from which the data are derived must be displayed (this enables users to obtain the record in PubMed). If the product/service/application retrieves data derived from MEDLINE/PubMed records and does provide a direct electronic link to the underlying record(s) in PubMed, there is no data element requirement for display.
2.Incorporate files that replace all previously distributed records (e.g., the annual MEDLINE/PubMed baseline files) no later than ninety (90) days after the date such files are made available to Licensee by NLM. Licensee shall make known, in a suitably clear and conspicuous manner, the currency of the NLM data used in its products/services/applications, based on the date NLM released the most recent data file used (i.e., the date NLM put the files on its server). [Also applies to Catfile, CatfilePlus, Serfile, CCRIS, ChemIDplus® Subset, HSDB®, GENE-TOX,TOXLINE® Subset]
3.Follow the NLM best practices recommendation that Licensees incorporate periodic update files containing new and/or maintained records, and remove deleted records, at least once every thirty (30) days after the date made available to Licensee. [Also applies to Catfile, CatfilePlus, and Serfile]
The following alternative to the best practices recommendation is permissible: If, at Licensee’s discretion, the suitability of Licensee’s product/service/application is not adversely affected by less frequent updates, updates may take place less frequently than every thirty (30) days. In this case, requirements in Appendix B still apply. If Licensee’s products/services/applications are updated during a calendar year but not within thirty (30) days after NLM makes new/maintained/deleted records available, Licensee shall make known in a suitably clear and conspicuous manner that the products/services/applications may not reflect the most current/accurate biomedical/scientific data available from NLM.
In either case, Licensee shall make known, in a suitably clear and conspicuous manner, the currency of the NLM data used in its products/services/applications, based on the date NLM released the most recent data file used (i.e., the date NLM put the files on its server).
4.Take reasonable steps to make known dosage errors in abstracts or retracted or partially retracted publications within thirty (30) days from the date such records are distributed by NLM. Recommended wording examples: “Published dosage error in abstract of PMID 1234567 is corrected in current version of the record.” “Article cited in PMID 1234567 is retracted (or partially retracted) by item cited in PMID 9876543.”
5.Perform updates and any value-added activity in such a way that no NLM-provided content becomes incorrect. [Also applies to Catfile, CatfilePlus, and Serfile, CCRIS, ChemIDplus Subset, HSDB, GENE-TOX, TOXLINE Subset]
6.Describe in a suitably clear and conspicuous manner the update frequency for Licensee’saddition of new records, application of maintained records, and removal of deleted records. [Also applies to Catfile, CatfilePlus, Serfile, CCRIS, ChemIDplus Subset, HSDB, GENE-TOX, TOXLINE Subset]
7.Take reasonable steps to prevent access to products/services/applications containing NLM data or data derived from NLM databases that have become superseded by updated and/or maintained versions. [Also applies to CCRIS, ChemIDplus Subset, HSDB, GENE-TOX, TOXLINE Subset]
APPENDIX C: MEDLINE®/PUBMED® MINIMAL DATA ELEMENT SET
The following elements, when present on the MEDLINE/PubMed record, are the minimal set required for display from Licensee’s products/services/applications when all of the following conditions exist:
1.Appendix B applies (that is, the Licensee’s products/services/applications are not based upon astatic version of the data).
2.Licensee’s product/service/application is a citation retrieval system displaying MEDLINE/PubMed citation data.
3.There is not a direct link from the data displayed to the corresponding record in PubMed at NLM. (If there is a direct link from the data displayed in the Licensee’s product/service/application to the record in PubMed at NLM, display of all elements below in Licensee’s product/service/application is not required.)
Elements with "X" in the Search Status column must be searchable.
Element Name | Element Meaning | Search Status |
AuthorList | Author(s) | X |
PubDate | Date of publication | |
DateRevised | Date record last revised*** | X |
Pagination | Pagination | |
ELocationID (optional if Pagination is present) | Electronic Location ID (DOI and/or PII) | |
MedlineTA | Journal title abbreviation* | X |
ArticleTitle | Title of article** | X |
PMID | Unique identifier*** | X |
Volume | Journal Volume | |
Comments/Corrections | Commentary, erratum, retraction, etc. |
*Full journal title (element name = Title) may be used instead.**Individual words in article title must be directly searchable. ***May be suppressed in publicly available applications but must be searchable internally (for quality assurance purposes).